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KDM4C 抗体 (C-Term)

KDM4C 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777688
发货至: 中国
  • 抗原 See all KDM4C 抗体
    KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
    抗原表位
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig
    宿主
    • 43
    克隆类型
    • 43
    多克隆
    标记
    • 18
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM4C antibody is un-conjugated
    应用范围
    • 31
    • 22
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    CLCNLRGGAL KQTKNNKWAH VMCAVAVPEV RFTNVPERTQ IDVGRIPLQR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against JMJD2C. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human JMJD2C
    Top Product
    Discover our top product KDM4C Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 813 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lu, Ward, Kapoor, Rohle, Turcan, Abdel-Wahab, Edwards, Khanin, Figueroa, Melnick, Wellen, ORourke, Berger, Chan, Levine, Mellinghoff, Thompson: "IDH mutation impairs histone demethylation and results in a block to cell differentiation." in: Nature, Vol. 483, Issue 7390, pp. 474-8, (2012) (PubMed).

  • 抗原
    KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))
    别名
    JMJD2C (KDM4C 产品)
    别名
    JMJD2C antibody, GASC1 antibody, JHDM3C antibody, TDRD14C antibody, bA146B14.1 antibody, 2410141F18Rik antibody, AA517467 antibody, Gasc1 antibody, Jmjd2c antibody, lysine demethylase 4C antibody, jumonji domain containing 2c antibody, lysine (K)-specific demethylase 4C antibody, KDM4C antibody, Jmjd2c antibody, kdm4c antibody, Kdm4c antibody
    背景
    JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
    Alias Symbols: FLJ25949, GASC1, JHDM3C, JMJD2C, KIAA0780, bA146B14.1
    Protein Interaction Partner: UBC, HIST2H3C, HDAC3, PPARG, HDAC1, H3F3A, HIST1H3A, KDM4C, KDM4A,
    Protein Size: 813
    分子量
    92 kDa
    基因ID
    23081
    NCBI登录号
    NM_001146695, NP_001140167
    UniProt
    F5H347
    途径
    Nuclear Hormone Receptor Binding, Warburg Effect
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