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KDM4B 抗体 (C-Term)

Cited in 1 publication. This 兔 多克隆 anti-KDM4B antibody specifically detects KDM4B in WB 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN952974
发货至: 中国
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Quick Overview for KDM4B 抗体 (C-Term) (ABIN952974)

抗原

See all KDM4B 抗体
KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This KDM4B antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 287-316, C-Term

    特异性

    This antibody recognizes Human and Mouse JMJD2B (Thr305)

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 287~316 amino acids from the C-terminal region of human JMJD2B

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

  • 抗原

    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

    别名

    JMJD2B / KDM4B

    背景

    Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.Synonyms: JHDM3B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KIAA0876, Lysine-specific demethylase 4B

    分子量

    121897 Da

    基因ID

    23030

    NCBI登录号

    NP_055830

    途径

    Warburg Effect
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