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KDM4B 抗体 (pThr305)

KDM4B 适用: 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386741
发货至: 中国
  • 抗原 See all KDM4B 抗体
    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
    抗原表位
    • 14
    • 12
    • 12
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr305
    适用
    • 90
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 86
    • 4
    克隆类型
    • 87
    • 3
    多克隆
    标记
    • 34
    • 11
    • 10
    • 10
    • 10
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM4B antibody is un-conjugated
    应用范围
    • 64
    • 64
    • 21
    • 19
    • 19
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human JMJD2B around the phosphorylation site of Thr305
    亚型
    IgG
    Top Product
    Discover our top product KDM4B Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
    别名
    JMJD2B (KDM4B 产品)
    别名
    KDM4B antibody, JMJD2B antibody, jmjd2b antibody, si:ch211-124a3.4 antibody, TDRD14B antibody, 4732474L06Rik antibody, Jmjd2b antibody, mKIAA0876 antibody, lysine demethylase 4B antibody, lysine (K)-specific demethylase 4B antibody, KDM4B antibody, kdm4b antibody, Kdm4b antibody
    背景

    Synonyms: KDM4B/JMJD2B phospho T305, KDM4B/JMJD2B phospho Thr305, p-KDM4BT305, p-KDM4BThr305, JHDM3B, JmjC domain-containing histone demethylation protein 3B, JMJD2B, JmjC domain-containing histone demethylation protein 3A, Jumonji domain containing protein 2B, KIAA0876, Lysine-specic demethylase 4B, KDM4B_HUMAN.

    Background: JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure, the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.

    基因ID
    23030
    途径
    Warburg Effect
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