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IREB2 抗体 (Middle Region)
IREB2
适用: 人
WB, IHC (p), FACS, EIA
宿主: 兔
Polyclonal
unconjugated
IREB2抗体详情
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抗原
See all IREB2 抗体
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
抗原表位
All epitopes for IREB2 抗体
AA 208-238, Middle Region
适用
All reactivities for IREB2 抗体
人
宿主
All hosts for IREB2 抗体
兔
克隆类型
All clonalities for IREB2 抗体
多克隆
标记
All conjugates for IREB2 抗体
This IREB2 antibody is un-conjugated
应用范围
All applications for IREB2 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes Human IREB2 (Center).
纯化方法
Protein A column, followed by peptide affinity purification
免疫原
KLH conjugated synthetic peptide between 208-238 amino acids from the Central region of human IREB2
亚型
Ig Fraction
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
IREB2目标详情
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抗原
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
别名
IREB2 (IREB2 产品 )
背景
IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.Synonyms: IRE-BP2, IRP2, Iron regulatory protein 2, Iron-responsive element-binding protein 2
分子量
105045 Da
基因ID
3658
NCBI登录号
NP_004127
途径
Transition Metal Ion Homeostasis
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