IREB2 抗体 (Middle Region)
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Quick Overview for IREB2 抗体 (Middle Region) (ABIN952944)
抗原
See all IREB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-238, Middle Region
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特异性
- This antibody recognizes Human IREB2 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 208-238 amino acids from the Central region of human IREB2
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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别名
- IREB2
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背景
- IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.Synonyms: IRE-BP2, IRP2, Iron regulatory protein 2, Iron-responsive element-binding protein 2
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分子量
- 105045 Da
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基因ID
- 3658
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NCBI登录号
- NP_004127
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途径
- Transition Metal Ion Homeostasis
抗原
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