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IREB2 抗体 (Middle Region)

IREB2 适用: 人, 大鼠, 小鼠, Pig, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778884
发货至: 中国
  • 抗原 See all IREB2 抗体
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 大鼠, 小鼠, Pig, 犬, 马, 豚鼠, 兔, 斑马鱼
    宿主
    • 42
    • 5
    • 1
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IREB2 antibody is un-conjugated
    应用范围
    • 34
    • 22
    • 18
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    IQINLNSIVP SVSGPKRPQD RVAVTDMKSD FQACLNEKVG FKGFQIAAEK
    预测反应
    Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against IREB2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human IREB2
    Top Product
    Discover our top product IREB2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 963 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    别名
    IREB2 (IREB2 产品)
    别名
    IREB2 antibody, im:7153062 antibody, DKFZp468N047 antibody, D9Ertd85e antibody, Irp2 antibody, ACO3 antibody, IRP2 antibody, IRP2AD antibody, IREBP2 antibody, iron responsive element binding protein 2 antibody, iron-responsive element binding protein 2 antibody, iron responsive element binding protein 2 L homeolog antibody, IREB2 antibody, ireb2 antibody, Ireb2 antibody, ireb2.L antibody
    背景
    IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
    Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD
    Protein Interaction Partner: RBCK1, UBC, FAM96A, FAM96B, CIAO1, FBXL5, UBA2, TNPO1, CBS, TERT, USP53, APP, PSMA3, VHL, YBX1,
    Protein Size: 963
    分子量
    105 kDa
    基因ID
    3658
    NCBI登录号
    NM_004136, NP_004127
    UniProt
    P48200
    途径
    Transition Metal Ion Homeostasis
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