IL-10 抗体 (Middle Region)
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- 抗原 See all IL-10 (IL10) 抗体
- IL-10 (IL10) (Interleukin 10 (IL10))
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抗原表位
- AA 33-62, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects human IL10.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
- 免疫原
- Synthetic peptide - KLH conjugated - corresponding to the center region (between 33-62aa) of human IL10.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product IL10 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- IL-10 (IL10) (Interleukin 10 (IL10))
- 别名
- Interleukin-10 / IL10 (IL10 产品)
- 背景
- Interleukin-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.Synonyms: CSIF, Cytokine synthesis inhibitory factor, IL-10, TGIF
- 基因ID
- 3586
- NCBI登录号
- NP_000563
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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