Integrin beta 7 抗体 (C-Term)
-
- 抗原 See all Integrin beta 7 (ITGB7) 抗体
- Integrin beta 7 (ITGB7)
-
抗原表位
- AA 736-765, C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Integrin beta 7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes Human Integrin beta-7 (C-term).
- 纯化方法
- Protein A column, followed by peptide affinity purification
- 免疫原
- KLH conjugated synthetic peptide between 736-765 amino acids from the C-terminal region of Human Integrin beta-7
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ITGB7 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- Integrin beta 7 (ITGB7)
- 别名
- Integrin beta-7 (ITGB7 产品)
- 背景
- Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.Synonyms: ITGB7, Integrin alpha 4 beta 7, Integrin beta-P, LPAM-1, LPAM1, M290 IEL antigen
- 分子量
- 86903 Da
- 基因ID
- 3695
- NCBI登录号
- NP_000880
- 途径
- Integrin Complex
-