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Integrin beta 7 抗体 (C-Term)

This anti-Integrin beta 7 antibody is a 兔 多克隆 antibody detecting Integrin beta 7 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952915
发货至: 中国

Quick Overview for Integrin beta 7 抗体 (C-Term) (ABIN952915)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

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  • 23
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宿主

  • 50
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  • 7
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克隆类型

  • 51
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多克隆

标记

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  • 1
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This Integrin beta 7 antibody is un-conjugated

应用范围

  • 40
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 9
    • 4
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    • 2
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    • 1
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    AA 736-765, C-Term

    特异性

    This antibody recognizes Human Integrin beta-7 (C-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 736-765 amino acids from the C-terminal region of Human Integrin beta-7

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta-7

    背景

    Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.Synonyms: ITGB7, Integrin alpha 4 beta 7, Integrin beta-P, LPAM-1, LPAM1, M290 IEL antigen

    分子量

    86903 Da

    基因ID

    3695

    NCBI登录号

    NP_000880

    途径

    Integrin Complex
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