HDAC11 抗体 (Middle Region)
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Quick Overview for HDAC11 抗体 (Middle Region) (ABIN952697)
抗原
See all HDAC11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 196-226, Middle Region
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特异性
- This antibody recognizes Human and Mouse HDAC11 (Center).
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交叉反应 (详细)
- Species reactivity (expected):Monkey.
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 196-226 amino acids from the Central region of human HDAC11
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HDAC11 (Histone Deacetylase 11 (HDAC11))
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别名
- HDAC11
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背景
- This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Cellular Location: Nucleus. Note=Predominantly nuclear. Tissue Location: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testisSynonyms: HD11, Histone deacetylase 11
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分子量
- 39183 Da
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基因ID
- 79885
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NCBI登录号
- NP_079103
抗原
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