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HDAC11 抗体 (N-Term)

HDAC11 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043840
发货至: 中国
  • 抗原 See all HDAC11 抗体
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 47-81, N-Term
    适用
    • 49
    • 43
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    • 5
    克隆类型
    • 60
    • 4
    多克隆
    标记
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC11 antibody is un-conjugated
    应用范围
    • 54
    • 33
    • 22
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    NFLKEEKLLS DSMLVEAREA SEEDLLVVHT RRYLN
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: histone deacetylase 11
    Protein Name: Histone deacetylase 11
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN), different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product HDAC11 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    别名
    HDAC11 (HDAC11 产品)
    别名
    CG31119 antibody, DHDACX antibody, Dmel\\CG31119 antibody, HDAC11 antibody, HDACX antibody, dHDAC11 antibody, dmHDA403 antibody, zgc:91942 antibody, HD11 antibody, histone deacetylase 11 antibody, Histone deacetylase 11 antibody, hypothetical protein antibody, HDAC11 antibody, hdac11 antibody, CpipJ_CPIJ001619 antibody, Bm1_15905 antibody, LOAG_18214 antibody, Hdac11 antibody
    背景
    Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.

    Synonyms: FLJ22237 antibody|HD 11 antibody|HD11 antibody|HDA11_HUMAN antibody|HDAC 11 antibody|HDAC11 antibody|Histone deacetylase 11 antibody
    基因ID
    79885
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