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GSTa2 抗体 (N-Term)

This anti-GSTa2 antibody is a 兔 多克隆 antibody detecting GSTa2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN952640
发货至: 中国

Quick Overview for GSTa2 抗体 (N-Term) (ABIN952640)

抗原

See all GSTa2 抗体
GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

适用

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  • 4
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宿主

  • 35
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克隆类型

  • 37
  • 3
多克隆

标记

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This GSTa2 antibody is un-conjugated

应用范围

  • 33
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 11
    • 9
    • 2
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    • 1
    • 1
    AA 1-30, N-Term

    特异性

    This antibody recognizes Human GSTA2 / GST2 (N-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human GSTA2 / GST2.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

    别名

    GSTA2 / GST2

    背景

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Synonyms: GST class-alpha member 2, GST-gamma, GSTA2-2, GTH2, Glutathione S-transferase A2, HA subunit 2

    基因ID

    2939

    NCBI登录号

    NP_000837
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