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GSTa2 抗体 (N-Term)

GSTa2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24006 unconjugated
产品编号 ABIN653362
发货至: 中国
  • 抗原 See all GSTa2 抗体
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    抗原表位
    • 14
    • 8
    • 7
    • 2
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 39
    • 3
    • 1
    宿主
    • 35
    • 4
    • 1
    克隆类型
    • 38
    • 2
    多克隆
    标记
    • 19
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSTa2 antibody is un-conjugated
    应用范围
    • 33
    • 24
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GSTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GSTA2.
    克隆位点
    RB24006
    亚型
    Ig Fraction
    Top Product
    Discover our top product GSTa2 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

    Li, Yuan, Li, Liu, Hua, Lu, Zhang: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." in: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).

  • 抗原
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    别名
    GSTA2 (GSTa2 产品)
    别名
    GSTA1 antibody, GST2 antibody, GSTA2-2 antibody, GTA2 antibody, GTH2 antibody, Gsta1 antibody, Gst2-2 antibody, Gstc-2 antibody, Gstc2 antibody, glutathione S-transferase alpha 2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 2 (Yc2) antibody, GSTA2 antibody, Gsta2 antibody
    背景
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
    分子量
    25664
    基因ID
    2939
    NCBI登录号
    NP_000837
    UniProt
    P09210
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