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GREM1 抗体 (C-Term)

GREM1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN952628
发货至: 中国
  • 抗原 See all GREM1 抗体
    GREM1 (Gremlin 1 (GREM1))
    抗原表位
    • 20
    • 15
    • 14
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 110-139, C-Term
    适用
    • 72
    • 40
    • 23
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 78
    • 8
    • 1
    克隆类型
    • 79
    • 8
    多克隆
    标记
    • 37
    • 14
    • 11
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GREM1 antibody is un-conjugated
    应用范围
    • 79
    • 45
    • 31
    • 13
    • 13
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human Gremlin-1 / GREM1 (C-term).
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of Human Gremlin-1 / GREM1
    亚型
    Ig Fraction
    Top Product
    Discover our top product GREM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GREM1 (Gremlin 1 (GREM1))
    别名
    Gremlin-1 / GREM1 (GREM1 产品)
    别名
    grem1 antibody, MGC136702 antibody, zgc:136702 antibody, GREM1 antibody, drm antibody, pig2 antibody, dand2 antibody, ihg-2 antibody, gremlin antibody, Cktsf1b1 antibody, Drm antibody, Grem antibody, ld antibody, gremlin-1 antibody, CKTSF1B1 antibody, DAND2 antibody, DRM antibody, GREMLIN antibody, IHG-2 antibody, cktsf1b1 antibody, gremlin 1a, DAN family BMP antagonist antibody, gremlin 1, DAN family BMP antagonist antibody, gremlin 1 antibody, gremlin 1, DAN family BMP antagonist L homeolog antibody, grem1a antibody, GREM1 antibody, LOC662541 antibody, grem1 antibody, Grem1 antibody, grem1.L antibody
    背景
    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1 BMP antagonist 1, DAN domain family member 2, DAND2, DRM, GREM-1, IHG-2, PIG2
    分子量
    20697 Da
    基因ID
    26585
    NCBI登录号
    NP_001178252
    途径
    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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