GREM1 抗体 (C-Term)
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Quick Overview for GREM1 抗体 (C-Term) (ABIN952628)
抗原
See all GREM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-139, C-Term
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特异性
- This antibody recognizes Human Gremlin-1 / GREM1 (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of Human Gremlin-1 / GREM1
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亚型
- Ig Fraction
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anti-Gremlin 1 (GREM1) (AA 101-184) antibody
GREM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 147-175), (C-Term) antibodyGREM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2060 unconjugated
anti-Gremlin 1 (GREM1) (AA 26-184) antibodyGREM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 25-184) antibodyGREM1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 26-184) antibodyGREM1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Gremlin 1 (GREM1) (AA 25-184) antibodyGREM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 75-184) antibodyGREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Gremlin 1 (GREM1) (AA 18-184) antibodyGREM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 27-184) antibodyGREM1 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 147-175), (C-Term) antibodyGREM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GREM1 (Gremlin 1 (GREM1))
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别名
- Gremlin-1 / GREM1
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背景
- This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1 BMP antagonist 1, DAN domain family member 2, DAND2, DRM, GREM-1, IHG-2, PIG2
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分子量
- 20697 Da
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基因ID
- 26585
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NCBI登录号
- NP_001178252
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途径
- Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
抗原
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