电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

GREM1 抗体 (C-Term)

This anti-GREM1 antibody is a 兔 多克隆 antibody detecting GREM1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952628
发货至: 中国

Quick Overview for GREM1 抗体 (C-Term) (ABIN952628)

抗原

See all GREM1 抗体
GREM1 (Gremlin 1 (GREM1))

适用

  • 85
  • 49
  • 23
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 90
  • 14
  • 1
  • 1

克隆类型

  • 91
  • 15
多克隆

标记

  • 52
  • 16
  • 12
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GREM1 antibody is un-conjugated

应用范围

  • 91
  • 47
  • 37
  • 21
  • 13
  • 13
  • 13
  • 8
  • 5
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 15
    • 13
    • 10
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 110-139, C-Term

    特异性

    This antibody recognizes Human Gremlin-1 / GREM1 (C-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of Human Gremlin-1 / GREM1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GREM1 (Gremlin 1 (GREM1))

    别名

    Gremlin-1 / GREM1

    背景

    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1 BMP antagonist 1, DAN domain family member 2, DAND2, DRM, GREM-1, IHG-2, PIG2

    分子量

    20697 Da

    基因ID

    26585

    NCBI登录号

    NP_001178252

    途径

    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
You are here:
Chat with us!