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DDIT3 抗体 (C-Term)

This anti-DDIT3 antibody is a 兔 多克隆 antibody detecting DDIT3 in WB, FACS 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN952424
发货至: 中国

Quick Overview for DDIT3 抗体 (C-Term) (ABIN952424)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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人, 小鼠

宿主

  • 126
  • 13

克隆类型

  • 114
  • 25
多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
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    AA 127-157, C-Term

    特异性

    This antibody recognizes DDIT3 (C-term).

    交叉反应 (详细)

    Species reactivity (expected):Human.
    Species reactivity (tested):Mouse.

    纯化方法

    Peptide Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 127-157 amino acids from the C-terminal region of Human DDIT3. Genename: DDIT3

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    GADD153 / CHOP

    背景

    This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.Synonyms: C/EBP-homologous protein, C/EBP-homologous protein 10, CHOP-10, CHOP10, DDIT-3, DDIT3, DNA damage-inducible transcript 3, Growth arrest and DNA-damage-inducible protein GADD153

    基因ID

    1649

    NCBI登录号

    NP_001181986

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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