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FZD6 抗体 (Middle Region)

This anti-FZD6 antibody is a 兔 多克隆 antibody detecting FZD6 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952410
发货至: 中国

Quick Overview for FZD6 抗体 (Middle Region) (ABIN952410)

抗原

See all FZD6 抗体
FZD6 (Frizzled Family Receptor 6 (FZD6))

适用

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宿主

  • 36
  • 2
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克隆类型

  • 39
  • 3
多克隆

标记

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This FZD6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
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    AA 493-520, Middle Region

    特异性

    This antibody recognizes Human FZD6 (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FZD6 (Frizzled Family Receptor 6 (FZD6))

    别名

    FZD6

    背景

    This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.Synonyms: Frizzled-6, Fz-6, hFz6

    分子量

    79292 Da

    基因ID

    8323

    NCBI登录号

    NP_001158087

    途径

    WNT signaling, Tube Formation
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