FDPS 抗体 (N-Term)
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Quick Overview for FDPS 抗体 (N-Term) (ABIN952387)
抗原
See all FDPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-82, N-Term
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特异性
- This antibody reacts to FDPS.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human FDPS
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FDPS (Farnesyl Diphosphate Synthase (FDPS))
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别名
- FPP Synthetase
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背景
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: FDPS, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthetase, KIAA1293
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分子量
- 48275 Da
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基因ID
- 2224
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NCBI登录号
- NP_001129293
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途径
- Regulation of Muscle Cell Differentiation
抗原
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