Dynamitin 抗体 (Middle Region)
Quick Overview for Dynamitin 抗体 (Middle Region) (ABIN952005)
抗原
See all Dynamitin (DCTN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 191-219, Middle Region
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特异性
- This antibody recognizes Human Dynactin subunit 2 (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of Human Dynactin subunit 2. Genename: DCTN2
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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别名
- Dynactin Subunit 2
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背景
- This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.Synonyms: 50 kDa dynein-associated polypeptide, DCTN2, DCTN50, Dynactin 2, Dynactin complex 50 kDa subunit, RBP50, p50 dynamitin
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分子量
- 44231 Da
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基因ID
- 10540
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NCBI登录号
- NP_006391
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途径
- M Phase, Ribonucleoprotein Complex Subunit Organization
抗原
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