DLL3 抗体 (C-Term)
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Quick Overview for DLL3 抗体 (C-Term) (ABIN951924)
抗原
See all DLL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 526-556, C-Term
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特异性
- This antibody recognizes DLL3 at C-term .
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a Protein A column followed by peptide affinity purification
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 526-556aa) of human DLL3.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DLL3 (delta Like Protein 3 (DLL3))
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别名
- DLL3
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背景
- Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.Synonyms: Delta-3, Delta-like protein 3
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基因ID
- 10683
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NCBI登录号
- NP_058637
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途径
- Notch Signaling
抗原
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