DENND1B 抗体 (N-Term)
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Quick Overview for DENND1B 抗体 (N-Term) (ABIN951885)
抗原
See all DENND1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-76, N-Term
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特异性
- This antibody recognizes Human DENND1B (N-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 46-76 amino acids from the N-terminal region of Human DENND1B. Genename: DENND1B
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
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别名
- DENND1B
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背景
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).Synonyms: C1orf218, Connecdenn 2, DENN domain-containing protein 1B, FAM31B
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分子量
- 48260 Da
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基因ID
- 163486
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NCBI登录号
- NP_001182144
抗原
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