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DENND1B 抗体 (N-Term)

DENND1B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28056 unconjugated
产品编号 ABIN654339
发货至: 中国
  • 抗原 See all DENND1B 抗体
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-68, N-Term
    适用
    • 31
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DENND1B antibody is un-conjugated
    应用范围
    • 39
    • 16
    • 15
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
    克隆位点
    RB28056
    亚型
    Ig Fraction
    Top Product
    Discover our top product DENND1B Primary Antibody
  • 应用备注
    WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    别名
    DENND1B (DENND1B 产品)
    别名
    C1ORF18 antibody, C1orf218 antibody, FAM31B antibody, 4632404N19Rik antibody, 4930467M19Rik antibody, 6820401H01Rik antibody, F730008N07Rik antibody, Fam31b antibody, si:ch211-195i21.1 antibody, DENN domain containing 1B antibody, DENN/MADD domain containing 1B antibody, DENND1B antibody, dennd1b antibody, Dennd1b antibody
    背景
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
    分子量
    86552
    基因ID
    163486
    NCBI登录号
    NP_001182144, NP_001182145, NP_659414
    UniProt
    Q6P3S1
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