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CPT1C 抗体 (C-Term)

This anti-CPT1C antibody is a 兔 多克隆 antibody detecting CPT1C in WB, FACS 和 EIA. Suitable for 人.
产品编号 ABIN951689
发货至: 中国

Quick Overview for CPT1C 抗体 (C-Term) (ABIN951689)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

适用

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宿主

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克隆类型

  • 52
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多克隆

标记

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This CPT1C antibody is un-conjugated

应用范围

  • 38
  • 28
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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
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    AA 759-790, C-Term

    特异性

    This antibody reacts to CPT1C.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 759-790 amino acids from the C-terminal region of human CPT1C

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

    别名

    CPT1C / CPT1-B

    背景

    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.Synonyms: CPT IC, Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1C, brain isoform

    分子量

    90989 Da

    基因ID

    126129

    NCBI登录号

    NP_001129524

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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