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CPT1C 抗体 (AA 752-782)

CPT1C 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030283
发货至: 中国
  • 抗原 See all CPT1C 抗体
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    抗原表位
    • 15
    • 12
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 752-782
    适用
    • 52
    • 6
    • 3
    宿主
    • 53
    • 1
    • 1
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 20
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPT1C antibody is un-conjugated
    应用范围
    • 46
    • 35
    • 13
    • 13
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 752-782 from the human protein was used as the immunogen for this CPT1C antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product CPT1C Primary Antibody
  • 应用备注
    Titration of the CPT1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the CPT1C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    别名
    CPT1C (CPT1C 产品)
    别名
    6530437J22Rik antibody, 9630004I06Rik antibody, CATL1 antibody, CPT1-B antibody, CPT1P antibody, CPTI-B antibody, CPTIC antibody, CPT IC antibody, carnitine palmitoyltransferase 1c antibody, carnitine palmitoyltransferase 1C antibody, Cpt1c antibody, CPT1C antibody
    背景
    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
    UniProt
    Q8TCG5
    途径
    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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