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Cortactin 抗体 (N-Term)

This anti-Cortactin antibody is a 兔 多克隆 antibody detecting Cortactin in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN951670
发货至: 中国

Quick Overview for Cortactin 抗体 (N-Term) (ABIN951670)

抗原

See all Cortactin (CTTN) 抗体
Cortactin (CTTN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cortactin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 16-46, N-Term

    特异性

    This antibody recognizes Cortactin (SRC8) at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Purified through a Protein A column followed by peptide affinity purification

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 16-46aa) of human Cortactin (SRC8)

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Cortactin (CTTN)

    别名

    Cortactin

    背景

    SRC8 (CTTN) is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1

    基因ID

    2017

    NCBI登录号

    NP_005222

    途径

    MAPK Pathway
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