Complement Factor B 抗体 (Middle Region)
Quick Overview for Complement Factor B 抗体 (Middle Region) (ABIN951644)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 474-504, Middle Region
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特异性
- This antibody reacts to CFB.
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交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 474~504 amino acids from the Center region of human CFB
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Complement Factor B (CFB)
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别名
- Complement Factor B
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背景
- CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
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分子量
- 85533 Da
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基因ID
- 629
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NCBI登录号
- NP_001701
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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