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Factor VII 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-Factor VII antibody is suitable to detect Factor VII in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN951602
发货至: 中国
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Quick Overview for Factor VII 抗体 (ABIN951602)

抗原

See all Factor VII (F7) 抗体
Factor VII (F7) (Coagulation Factor VII (F7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Factor VII antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

AA-3
  • 特异性

    This antibody is specific for factor VII/VIIa (AA-3).

    交叉反应 (详细)

    Also reacts to: VIIa

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Human Factor VII (AA-3) purified from plasma.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide (NaN3) as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." in: British journal of haematology, (2016) (PubMed).

  • 抗原

    Factor VII (F7) (Coagulation Factor VII (F7))

    背景

    Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

    基因ID

    2155

    NCBI登录号

    NP_000122

    UniProt

    P08709

    途径

    Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
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