CD99 抗体
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- 抗原 See all CD99 抗体
- CD99
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD99 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Protein-A affinity chromatography
- 免疫原
- Human thymocytes
- 克隆位点
- 3B2-TA8
- 亚型
- IgG2a
- Top Product
- Discover our top product CD99 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL (> 95% pure by SDS-PAGE)
- 缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CD99
- 别名
- CD99 / MIC2 (CD99 产品)
- 物质类
- Viral Protein
- 背景
- CD99 is a ubiquitous transmembrane type I sialoglycoprotein of a unique and poorly characterized protein family. CD99 is heavily O-glycosylated and was described as a T cell costimulator and strong activator of integrin-mediated actin cytoskeleton assembly, promoting cell adhesion and homotypic aggregation, immediate arrest on an inflamed vascular endothelium, and cell migration through it. Ligation of CD99 under some conditions can lead to apoptosis. Originally CD99 was described as a human thymus leukemia antigen, an Ewing´s sarcoma-specific membrane marker, and an adhesion molecule involved in spontaneous rosette formation of T cells with erythrocytes.Synonyms: 12E7, E2 antigen, MIC2X, MIC2Y, Protein MIC2, T-cell surface glycoprotein E2
- 基因ID
- 4267
- NCBI登录号
- NP_001116370
- UniProt
- P14209
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