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CD99 抗体

This anti-CD99 antibody is a 小鼠 单克隆 antibody detecting CD99 in FACS. Suitable for 人.
产品编号 ABIN951444
发货至: 中国

Quick Overview for CD99 抗体 (ABIN951444)

抗原

See all CD99 抗体
CD99

适用

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宿主

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小鼠

克隆类型

  • 89
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单克隆

标记

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This CD99 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

3B2-TA8
  • 特异性

    This antibody recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Human thymocytes

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL (> 95% pure by SDS-PAGE)

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD99

    别名

    CD99 / MIC2

    背景

    CD99 is a ubiquitous transmembrane type I sialoglycoprotein of a unique and poorly characterized protein family. CD99 is heavily O-glycosylated and was described as a T cell costimulator and strong activator of integrin-mediated actin cytoskeleton assembly, promoting cell adhesion and homotypic aggregation, immediate arrest on an inflamed vascular endothelium, and cell migration through it. Ligation of CD99 under some conditions can lead to apoptosis. Originally CD99 was described as a human thymus leukemia antigen, an Ewing´s sarcoma-specific membrane marker, and an adhesion molecule involved in spontaneous rosette formation of T cells with erythrocytes.Synonyms: 12E7, E2 antigen, MIC2X, MIC2Y, Protein MIC2, T-cell surface glycoprotein E2

    基因ID

    4267

    NCBI登录号

    NP_001116370

    UniProt

    P14209
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