C5AR1 抗体 (Biotin)
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- 抗原 See all C5AR1 抗体
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This C5AR1 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.
- 纯化方法
- Affinity chromatography on Protein G
- 免疫原
- RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface Donor: Lou/c rat spleen cells
- 克隆位点
- 8D6
- 亚型
- IgG2a
- Top Product
- Discover our top product C5AR1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0,1 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- 别名
- CD88 / C5R1 (C5AR1 产品)
- 背景
- Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
- 基因ID
- 728
- NCBI登录号
- NP_001727
- UniProt
- P21730
- 途径
- Complement System
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