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CD80 抗体

This anti-CD80 antibody is a 大鼠 单克隆 antibody detecting CD80 in FACS. Suitable for 小鼠.
产品编号 ABIN951411
发货至: 中国

Quick Overview for CD80 抗体 (ABIN951411)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

  • 97
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大鼠

克隆类型

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单克隆

标记

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This CD80 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

RMMP-1
  • 特异性

    This antibody recognises the murine CD80 cell surface protein, also known as B7-1.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Purified

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and EIA grade BSA to bring total protein concentration to 4-5 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 is a member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

    基因ID

    12519

    NCBI登录号

    NP_033985

    UniProt

    Q00609

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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