P-Selectin 抗体 (FITC)
-
- 抗原 See all P-Selectin (SELP) 抗体
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
-
适用
- 人, 灵长类
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This P-Selectin antibody is conjugated to FITC
-
应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes CD62P (P-selectin), a 140 kDa single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes, it is relocated to the plasma membrane upon activation.
- 交叉反应 (详细)
- Species reactivity (tested):Human, Non-Human Primates
- 免疫原
- Human platelets
- 克隆位点
- AK4
- 亚型
- IgG1
- Top Product
- Discover our top product SELP Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
- 储存条件
- 4 °C
-
- 抗原
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- 别名
- CD62P / P-Selectin (SELP 产品)
- 背景
- CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
- 基因ID
- 6403
- NCBI登录号
- NP_002996
- UniProt
- P16109
-