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CD5 抗体 (Biotin)

This anti-CD5 antibody is a 大鼠 单克隆 antibody detecting CD5 in FACS. Suitable for 人 和 小鼠.
产品编号 ABIN951342
发货至: 中国

Quick Overview for CD5 抗体 (Biotin) (ABIN951342)

抗原

See all CD5 抗体
CD5

适用

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人, 小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD5 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

03-07-53
  • 特异性

    This CD5 (Ly-1) Monoclonal Antibody is specific for the Mouse CD5 antigen.

    纯化方法

    Protein G Chromatography

    免疫原

    Mouse thymus or spleen from Balb/c mouse thymus or spleen.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) -20 °C for longer.
  • 抗原

    CD5

    别名

    CD5

    背景

    CD5 is a 55 kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.Synonyms: CD5, LEU1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5

    基因ID

    12507

    NCBI登录号

    NP_031676

    UniProt

    P13379
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