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CD5 抗体 (AA 269-366)

CD5 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal CD5-2416 unconjugated
产品编号 ABIN6941056
发货至: 中国
  • 抗原 See all CD5 抗体
    CD5
    抗原表位
    • 16
    • 9
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    • 5
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    • 2
    • 1
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    AA 269-366
    适用
    • 221
    • 90
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    • 11
    • 10
    • 5
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    宿主
    • 166
    • 81
    • 56
    • 1
    小鼠
    克隆类型
    • 232
    • 70
    单克隆
    标记
    • 109
    • 38
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    • 28
    • 13
    • 8
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    This CD5 antibody is un-conjugated
    应用范围
    • 235
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    • 66
    • 65
    • 53
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)
    克隆位点
    CD5-2416
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD5 Primary Antibody
  • 应用备注

    Positive Control: 293T, Ramos or MOLT-4 cells. Tonsil or Lymph Node.

    Known Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD5
    别名
    CD5 (CD5 产品)
    别名
    CD5 antibody, Ly-1 antibody, Ly-12 antibody, Ly-A antibody, Lyt-1 antibody, LEU1 antibody, T1 antibody, CD5 molecule antibody, CD5 antigen antibody, CD5 molecule like antibody, Cd5 molecule antibody, CD5 antibody, Cd5 antibody, CD5L antibody
    分子量
    67kDa
    基因ID
    921
    UniProt
    P06127
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