IGSF8 抗体 (Middle Region)
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Quick Overview for IGSF8 抗体 (Middle Region) (ABIN951296)
抗原
See all IGSF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 233-262, Middle Region
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特异性
- This antibody detects IGSF8 (Center).
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse
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纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
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免疫原
- Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
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别名
- CD316 / IGSF8
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背景
- GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.Synonyms: CD81 partner 3, CD81P3, EWI2, Glu-Trp-Ile EWI motif-containing protein 2, Immunoglobulin superfamily member 8, KCT4, Keratinocytes-associated transmembrane protein 4, LIR-D1
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基因ID
- 93185
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NCBI登录号
- NP_001193594
抗原
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