IGSF8 抗体 (Middle Region)
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北京 101111
Quick Overview for IGSF8 抗体 (Middle Region) (ABIN2788247)
抗原
See all IGSF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- IGSF8 Antibody - middle region
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序列
- LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 83%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%
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产品特性
- This is a rabbit polyclonal antibody against IGSF8. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human IGSF8
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59875-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
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别名
- IGSF8
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背景
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Background Information: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Gene Name: Immunoglobulin superfamily, member 8
Alternative Symbols: EWI2, PGRL, CD316, EWI-2, KCT-4, CD81P3, LIR-D1
Protein Name: Immunoglobulin superfamily member 8
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分子量
- 65kDa
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基因ID
- 93185
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NCBI登录号
- NP_443100
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UniProt
- Q969P0
抗原
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