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TLR4 抗体 (Middle Region)

This anti-TLR4 antibody is a 兔 多克隆 antibody detecting TLR4 in WB 和 EIA. Suitable for 人.
产品编号 ABIN951278
发货至: 中国

Quick Overview for TLR4 抗体 (Middle Region) (ABIN951278)

抗原

See all TLR4 抗体
TLR4 (Toll-Like Receptor 4 (TLR4))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 676-706, Middle Region

    特异性

    This antibody detects CD284 / TLR4 (Center).

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A column followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 676~706 amino acids from the Central region of human TLR4

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原

    TLR4 (Toll-Like Receptor 4 (TLR4))

    别名

    CD284 / TLR4

    背景

    TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.Synonyms: Toll-like receptor 4

    基因ID

    7099

    NCBI登录号

    NP_612564

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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