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CD226 抗体 (FITC)

CD226 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 15F-10E5 FITC
产品编号 ABIN951229
发货至: 中国
  • 抗原 See all CD226 抗体
    CD226
    适用
    • 68
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 51
    • 21
    • 3
    大鼠
    克隆类型
    • 45
    • 29
    • 1
    单克隆
    标记
    • 48
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD226 antibody is conjugated to FITC
    应用范围
    • 39
    • 29
    • 27
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
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    Flow Cytometry (FACS)
    特异性
    Recent experiments show that this antibody (clone 15F.10E5) only binds to differentiated Th1 cells but not Th2 or Th0 cells. It also suppressed both antigen-specific T cell expansion and an autoimmune disease (EAE) mediated by effector Th1 cells.
    免疫原
    AE7 cells Donor: Lewis rat Fusion Partner: SP 2/0 myeloma
    克隆位点
    15F-10E5
    亚型
    IgM
    Top Product
    Discover our top product CD226 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0,1 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD226
    别名
    CD226 / DNAM1 (CD226 产品)
    背景
    CD226 (also called DNAM-1) is constituitively expressed on naive CD8+ T cells, as well as subsets of naive CD11b+ macrophages and NK cells. It is also found on a lower percentage (~40 % ) of unactivated CD4+ T cells. CD226 is functional upon T cell activation, and CD226 ligands (CD112 and CD155) are the same in the mouse as for human (Tage-4 is the mouse homologue of CD155). The gene for mouse DNAM-1 was identified on chromosome 18, and the predicted amino acid sequence shows a 53 % homology with human DNAM-1.Synonyms: DNAM-1, DNAX accessory molecule 1
    基因ID
    225825
    NCBI登录号
    NP_848802
    UniProt
    Q8K4F0
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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