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CD226 抗体 (FITC)

This anti-CD226 antibody is a 大鼠 单克隆 antibody detecting CD226 in FACS. Suitable for 小鼠.
产品编号 ABIN951229
发货至: 中国

Quick Overview for CD226 抗体 (FITC) (ABIN951229)

抗原

See all CD226 抗体
CD226

适用

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小鼠

宿主

  • 61
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  • 10
大鼠

克隆类型

  • 54
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  • 1
单克隆

标记

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This CD226 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

15F-10E5
  • 特异性

    Recent experiments show that this antibody (clone 15F.10E5) only binds to differentiated Th1 cells but not Th2 or Th0 cells. It also suppressed both antigen-specific T cell expansion and an autoimmune disease (EAE) mediated by effector Th1 cells.

    免疫原

    AE7 cells Donor: Lewis rat Fusion Partner: SP 2/0 myeloma

    亚型

    IgM
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0,1 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD226

    别名

    CD226 / DNAM1

    背景

    CD226 (also called DNAM-1) is constituitively expressed on naive CD8+ T cells, as well as subsets of naive CD11b+ macrophages and NK cells. It is also found on a lower percentage (~40 % ) of unactivated CD4+ T cells. CD226 is functional upon T cell activation, and CD226 ligands (CD112 and CD155) are the same in the mouse as for human (Tage-4 is the mouse homologue of CD155). The gene for mouse DNAM-1 was identified on chromosome 18, and the predicted amino acid sequence shows a 53 % homology with human DNAM-1.Synonyms: DNAM-1, DNAX accessory molecule 1

    基因ID

    225825

    NCBI登录号

    NP_848802

    UniProt

    Q8K4F0

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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