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TEK 抗体 (AA 23-737)

TEK 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951225
发货至: 中国
  • 抗原 See all TEK 抗体
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    抗原表位
    • 19
    • 19
    • 16
    • 9
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    • 1
    • 1
    • 1
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    AA 23-737
    适用
    • 131
    • 65
    • 49
    • 22
    • 4
    • 3
    小鼠
    宿主
    • 122
    • 17
    • 3
    • 2
    • 2
    克隆类型
    • 128
    • 18
    多克隆
    标记
    • 69
    • 9
    • 8
    • 5
    • 5
    • 5
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    • 4
    • 3
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    • 3
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    • 1
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    This TEK antibody is un-conjugated
    应用范围
    • 74
    • 54
    • 40
    • 40
    • 31
    • 27
    • 14
    • 13
    • 12
    • 8
    • 8
    • 6
    • 4
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    • 1
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    Western Blotting (WB)
    特异性
    Recognizes TIE-2 (CD202b/TEK)
    交叉反应 (详细)
    Species reactivity (tested):Mouse, Human (Weak).
    纯化方法
    Protein A Chromatography
    免疫原
    Highly pure (>95%) recombinant Mouse soluble TIE-2 (Ala23-Ala737) derived from Insect cells.
    亚型
    IgG
    Top Product
    Discover our top product TEK Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!
    有效期
    6 months
  • 抗原
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    别名
    CD202b / TEK (TEK 产品)
    别名
    TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
    背景
    Recombinant Mouse soluble TIE-1 was fused with a 6x His-tag at the C-terminus. The soluble receptor protein consists of the full extracellular domain (Ser22-Ala748). Mouse sTIE-1 monomer has a calculated molecular mass of approximately 79,8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 95 kDa protein in SDS-PAGE under reducing conditions. TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
    基因ID
    7010
    NCBI登录号
    NP_000450
    途径
    RTK signaling, Growth Factor Binding
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