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TEK 抗体 (AA 23-737)

This anti-TEK antibody is a 兔 多克隆 antibody detecting TEK in WB. Suitable for 小鼠.
产品编号 ABIN951225
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TEK 抗体 (AA 23-737) (ABIN951225)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

  • 132
  • 63
  • 48
  • 21
  • 3
  • 3
小鼠

宿主

  • 118
  • 24
  • 5
  • 3
  • 2
  • 1
  • 1

克隆类型

  • 124
  • 30
多克隆

标记

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This TEK antibody is un-conjugated

应用范围

  • 78
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  • 40
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  • 34
  • 32
  • 14
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  • 12
  • 9
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Western Blotting (WB)
  • 抗原表位

    • 20
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    AA 23-737

    特异性

    Recognizes TIE-2 (CD202b/TEK)

    交叉反应 (详细)

    Species reactivity (tested):Mouse, Human (Weak).

    纯化方法

    Protein A Chromatography

    免疫原

    Highly pure (>95%) recombinant Mouse soluble TIE-2 (Ala23-Ala737) derived from Insect cells.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.2

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!

    有效期

    6 months
  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    CD202b / TEK

    背景

    Recombinant Mouse soluble TIE-1 was fused with a 6x His-tag at the C-terminus. The soluble receptor protein consists of the full extracellular domain (Ser22-Ala748). Mouse sTIE-1 monomer has a calculated molecular mass of approximately 79,8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 95 kDa protein in SDS-PAGE under reducing conditions. TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

    基因ID

    7010

    NCBI登录号

    NP_000450

    途径

    RTK signaling, Growth Factor Binding
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