TEK 抗体 (AA 19-745)
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北京 101111
Quick Overview for TEK 抗体 (AA 19-745) (ABIN951222)
抗原
See all TEK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-745
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特异性
- Recognizes TIE-2 (CD202b/TEK)
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Protein A Chromatography
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免疫原
- Highly pure (>95%) recombinant Human soluble TIE-2 (Thr19-Lys745) derived from Insect cells.
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亚型
- IgG
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anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 66-185) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 571-748) antibodyTEK 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5B9 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789) antibodyTEK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 401-550) antibodyTEK 适用: 人, 小鼠, 大鼠, Cow ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 286-465) antibodyTEK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 500-750) antibodyTEK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (C-Term) antibodyTEK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789), (C-Term) antibodyTEK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01525-01526 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2
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储存条件
- 4 °C/-20 °C
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储存方法
- The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!
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有效期
- 6 months
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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别名
- CD202b / TEK
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背景
- TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/TEK comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Two ligands, angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2), which bind TIE-2 with high affinity have been identified. Ang2 has been reported to act as an antagonist for Ang1. Mice engineered to overexpress Ang2 or to lack Ang1 or TIE-2 display similar angiogenic defects.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
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基因ID
- 7010
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NCBI登录号
- NP_000450
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途径
- RTK signaling, Growth Factor Binding
抗原
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