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BST1 抗体

This anti-BST1 antibody is a 大鼠 单克隆 antibody detecting BST1 in FACS. Suitable for 小鼠.
产品编号 ABIN951197
发货至: 中国

Quick Overview for BST1 抗体 (ABIN951197)

抗原

See all BST1 抗体
BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This BST1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

KT157
  • 特异性

    This Monoclonal Antibody reacts with Mouse CD157.

    纯化方法

    Protein G Chromatography

    免疫原

    T cell hybridoma J774. Donor: Balb/c mouse spleen cells. Fusion Partner: NSO Mouse Myelom a Partner.

    亚型

    IgG2c
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

    别名

    CD157 / BST1

    背景

    CD157 also known as BP-3 Alloantigen or Bone marrow Stromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2

    基因ID

    12182

    NCBI登录号

    NP_033893

    UniProt

    Q64277
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