BST1
适用: 人
FACS
宿主: 兔
Chimeric
unconjugated
Fc fragment
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS containing 0.02 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
BST1
(Bone Marrow Stromal Cell Antigen 1 (BST1))
别名
CD157 / BST1
背景
CD157 also known as BP-3 Alloantigen or Bone marrow Stromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2