Calpain 6 抗体 (Middle Region)
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Quick Overview for Calpain 6 抗体 (Middle Region) (ABIN951010)
抗原
See all Calpain 6 (CAPN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 289-319, Middle Region
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特异性
- This antibody reacts to CAPN6.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 289-319 amino acids from the Central region of human CAPN6
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Calpain 6 (CAPN6)
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别名
- Calpain-6
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背景
- Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin
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分子量
- 74576 Da
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基因ID
- 827
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NCBI登录号
- NP_055104
抗原
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