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Calpain 6 抗体 (Middle Region)

This anti-Calpain 6 antibody is a 兔 多克隆 antibody detecting Calpain 6 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN951010
发货至: 中国

Quick Overview for Calpain 6 抗体 (Middle Region) (ABIN951010)

抗原

See all Calpain 6 (CAPN6) 抗体
Calpain 6 (CAPN6)

适用

  • 31
  • 7
  • 4

宿主

  • 28
  • 4

克隆类型

  • 28
  • 4
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Calpain 6 antibody is un-conjugated

应用范围

  • 22
  • 17
  • 16
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 289-319, Middle Region

    特异性

    This antibody reacts to CAPN6.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 289-319 amino acids from the Central region of human CAPN6

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Calpain 6 (CAPN6)

    别名

    Calpain-6

    背景

    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin

    分子量

    74576 Da

    基因ID

    827

    NCBI登录号

    NP_055104
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