BPNT1 抗体 (C-Term)
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北京 101111
Quick Overview for BPNT1 抗体 (C-Term) (ABIN950676)
抗原
See all BPNT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 276-305, C-Term
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特异性
- This antibody reacts to BPNT1.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human BPNT1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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别名
- BPNT1
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背景
- BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.Synonyms: 3'(2'), 4-phosphatase, 5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol-1
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基因ID
- 10380
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NCBI登录号
- NP_006076
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途径
- Inositol Metabolic Process
抗原
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