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BPNT1 抗体

The 兔 多克隆 anti-BPNT1 antibody (ABIN2856006) specifically detects BPNT1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2856006
发货至: 中国
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Quick Overview for BPNT1 抗体 (ABIN2856006)

抗原

See all BPNT1 抗体
BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BPNT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)
    BPNT1 antibody [N1C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse liver , HeLaS3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.7 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

    别名

    3'(2'), 5'-bisphosphate nucleotidase 1

    背景

    BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

    分子量

    33 kDa

    基因ID

    10380

    UniProt

    O95861

    途径

    Inositol Metabolic Process
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