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BAG4 抗体 (C-Term)

BAG4 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN950598
发货至: 中国
  • 抗原 See all BAG4 抗体
    BAG4 (BCL2-Associated Athanogene 4 (BAG4))
    抗原表位
    • 13
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-409, C-Term
    适用
    • 53
    • 17
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 48
    • 4
    • 3
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BAG4 antibody is un-conjugated
    应用范围
    • 38
    • 24
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BAG4.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 380-409 amino acids from the C-terminal region of human BAG4
    亚型
    Ig Fraction
    Top Product
    Discover our top product BAG4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BAG4 (BCL2-Associated Athanogene 4 (BAG4))
    别名
    BAG4 (BAG4 产品)
    别名
    BAG-4 antibody, SODD antibody, BAG4 antibody, fd20a04 antibody, wu:fd20a04 antibody, si:dkey-220o5.3 antibody, 2410112I15Rik antibody, ATBAG4 antibody, BCL-2-associated athanogene 4 antibody, BCL2 associated athanogene 4 antibody, BCL2-associated athanogene 4 antibody, BCL-2-associated athanogene 4 antibody, BAG4 antibody, Bag4 antibody, bag4 antibody
    背景
    BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.Synonyms: BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, SODD, Silencer of death domains
    基因ID
    9530
    NCBI登录号
    NP_004865
    途径
    Regulation of Actin Filament Polymerization
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