CHN2 抗体 (Middle Region)
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Quick Overview for CHN2 抗体 (Middle Region) (ABIN950491)
抗原
See all CHN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 162-192, Middle Region
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特异性
- This antibody detects ARHGAP3/CHN2.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse
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纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the central region ( between 162-192aa) of human CHN2.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CHN2 (Chimerin (Chimaerin) 2 (CHN2))
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别名
- ARHGAP3 / CHN2
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背景
- The CHN2 gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: BCH, Beta-chimaerin, Beta-chimerin, Rho GTPase-activating protein 3
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基因ID
- 1124
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NCBI登录号
- NP_001035025
抗原
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