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ANAPC5 抗体 (Middle Region)

The 兔 多克隆 anti-ANAPC5 antibody (ABIN950454) specifically detects ANAPC5 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN950454
发货至: 中国
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Quick Overview for ANAPC5 抗体 (Middle Region) (ABIN950454)

抗原

See all ANAPC5 抗体
ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

适用

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宿主

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克隆类型

  • 54
多克隆

标记

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This ANAPC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 156-185, Middle Region

    特异性

    This antibody reacts to APC5.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

    别名

    APC5 / ANAPC5

    背景

    This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.Synonyms: Anaphase-promoting complex subunit 5, Cyclosome subunit 5

    基因ID

    51433

    NCBI登录号

    NP_057321

    途径

    M Phase
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