Androgen Receptor 抗体 (Middle Region)
Quick Overview for Androgen Receptor 抗体 (Middle Region) (ABIN950408)
抗原
See all Androgen Receptor (AR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 281-309, Middle Region
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特异性
- This antibody reacts to Androgen receptor.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 281-309 amino acids from the Central region of human AR
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亚型
- Ig Fraction
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anti-Androgen Receptor (AR) antibody
AR 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (N-Term) antibodyAR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) antibodyAR 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Androgen Receptor (AR) antibodyAR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 491-679) antibodyAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Androgen Receptor (AR) (N-Term) antibodyVerified AR 适用: 人 WB, IHC, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 221-320) antibodyAR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Androgen Receptor (AR) (AA 15-246) antibodyAR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 365-392) antibodyAR 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 825-919) antibodyAR 适用: 人, 小鼠, 大鼠, Pig, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Androgen Receptor (AR)
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别名
- Androgen Receptor
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背景
- The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].Synonyms: DHTR, Dihydrotestosterone receptor, NR3C4, Nuclear receptor subfamily 3 group C member 4
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基因ID
- 367
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NCBI登录号
- NP_000035
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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