Ensa 抗体 (Middle Region)
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Quick Overview for Ensa 抗体 (Middle Region) (ABIN950376)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-74, Middle Region
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特异性
- This antibody recognizes Human and Mouse Alpha-endosulfine (ENSA) (Center).
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 46-74 amino acids from the Central region of Human ENSA.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- alpha-Endosulfine (ENSA)
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背景
- ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes.Synonyms: ARPP-19e
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分子量
- 13389 Da
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基因ID
- 2029
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NCBI登录号
- NP_004427
抗原
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