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AIRE 抗体 (Middle Region)

The 兔 多克隆 anti-AIRE antibody (ABIN950316) specifically detects AIRE in WB, IF 和 EIA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN950316
发货至: 中国
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Quick Overview for AIRE 抗体 (Middle Region) (ABIN950316)

抗原

See all AIRE 抗体
AIRE (Autoimmune Regulator (AIRE))

适用

  • 51
  • 22
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
人, 小鼠

宿主

  • 47
  • 6
  • 1

克隆类型

  • 53
多克隆

标记

  • 38
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AIRE antibody is un-conjugated

应用范围

  • 38
  • 26
  • 19
  • 8
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 64-92, Middle Region

    特异性

    This antibody reacts to AIRE.

    交叉反应 (详细)

    Species reactivity (tested):Human and Mouse.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    AIRE (Autoimmune Regulator (AIRE))

    别名

    AIRE / APECED

    背景

    This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).Synonyms: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator

    基因ID

    326

    NCBI登录号

    NP_000374

    途径

    Chromatin Binding
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