DAXX 抗体 (AA 558-740)
(1 reference)Quick Overview for DAXX 抗体 (AA 558-740) (ABIN94302)
抗原
See all DAXX 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 558-740
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原理
- Anti-DAXX Purified
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特异性
- The mouse monoclonal antibody DAXX-01 recognizes Daxx, a cytoplasmic death domain containing protein mainly expressed in fetal and adult human and mouse tissue.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant C-terminal part (aa 558-740) of human Daxx.
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亚型
- IgG1
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anti-Death-Domain Associated Protein (DAXX) (AA 561-660) antibody
DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 56-345) antibodyDAXX 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (C-Term) antibodyDAXX 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer213) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer495) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 1-740) antibodyDAXX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 580-740) antibodyDAXX 适用: 人 WB, ICC, IP 宿主: 小鼠 Monoclonal DAXX-03 unconjugated
anti-Death-Domain Associated Protein (DAXX) (Center) antibodyDAXX 适用: 人, 猴 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Requirement for Daxx in mature T-cell proliferation and activation." in: Cell death and differentiation, Vol. 14, Issue 4, pp. 795-806, (2007) (PubMed).
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: "Requirement for Daxx in mature T-cell proliferation and activation." in: Cell death and differentiation, Vol. 14, Issue 4, pp. 795-806, (2007) (PubMed).
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- DAXX (Death-Domain Associated Protein (DAXX))
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别名
- DAXX
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背景
- Death domain associated protein,Daxx is an apoptosis-modulating death domain-associated protein with functions in transcriptional regulation. Daxx functions both in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).,DAP6, EAP1, BING2
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基因ID
- 1616
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UniProt
- Q9UER7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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