电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

P-Selectin 抗体

SELP 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal HI62P unconjugated
产品编号 ABIN94212
发货至: 中国
  • 抗原 See all P-Selectin (SELP) 抗体
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    适用
    • 110
    • 36
    • 32
    • 21
    • 13
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 69
    • 57
    • 1
    • 1
    小鼠
    克隆类型
    • 66
    • 62
    单克隆
    标记
    • 56
    • 17
    • 15
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P-Selectin antibody is un-conjugated
    应用范围
    • 82
    • 69
    • 29
    • 29
    • 29
    • 25
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody HI62P recognizes an extracellular epitope of CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes, it is relocated to the plasma membrane upon activation.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human platelets
    克隆位点
    HI62P
    亚型
    IgG1
    Top Product
    Discover our top product SELP Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    别名
    CD62P (SELP 产品)
    别名
    PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
    背景
    Selectin P,CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.,P-selectin, GMP140, SELP, PADGEM, GRMP, LECAM3, PSEL
    基因ID
    6403
    UniProt
    P16109
You are here:
客服